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内容大纲
天然药物化学是指运用现代科学理论与方法研究天然药物中具有生理活性成分的药学/化学分支学科。本课程是高等院校中药学、药学、制药工程等专业的必修或主要专业课程,其涵盖的专业知识涉及药物的研发、生产和监管的各个环节,特别是在创新药物分子的发现、中药或民族药物现代化等领域发挥着不可替代的作用。 -
作者介绍
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目录
1 Introduction
1.1 Brief introduction
1.2 Biosynthesis of natural compounds
1.3 Extraction and isolation methods
1.4 The methods of structure research
References
2 Saccharides and Glycosides
2.1 Introduction
2.2 Stereochemistry of monosaccharide
2.3 Classification of saccharides and glycosides
2.4 Chemical properties of saccharides
2.5 Cleavage of glycosidic bond
2.6 The NMR properties of saccharides
2.7 The structure determination of saccharide chain
2.8 The extraction and isolation of saccharides and glycosides
References
3 Phenylpropanoids
3.1 Introduction
3.2 Biosynthesis pathway
3.3 Phenylpropionic acid
3.4 Coumarins
3.5 Lignans
References
4 Quinones
4.1 Introduction
4.2 Biosynthesis pathway
4.3 Structure types
4.4 Physicochemical properties
4.5 Extraction and isolation
4.6 Spectral characteristic
4.7 Bioactivities
4.8 Example of structure elucidation
References
5 Flavonoids
5.1 Structure category of flavonoids
5.2 Physical, chemical properties, and color reaction
5.3 Extraction and isolation
5.4 Identification and structure characterization of flavonoids
5.5 Biological activity of flavonoids
References
6 Terpenoids and Volatile Oils
6.1 Introduction
6.2 Structure types and representation
6.3 Physicochemical properties of terpenoids
6.4 Extraction and isolation of terpenoids
6.5 Structure elucidation of terpenoids
6.6 Volatile oils
References
7 Triterpenoids and Their Glycosides
7.1 Introduction
7.2 Biosynthesis pathway
7.3 Structure types
7.4 Physicochemical properties
7.5 Extraction and isolation
7.6 Spectral characteristics
7.7 Bioactivities
7.8 Examples of structure elucidation
References
8 Steroids and Their Glycosides
8.1 Introduction
8.2 Steroidal saponins
8.3 C2 steroids
8.4 Cardioactive glycosides
8.5 Extraction and separation of steroids
References
9 Alkaloids
9.1 Introduction
9.2 Biosynthesis pathway
9.3 Structure types
9.4 Physicochemical properties
9.5 Extraction and isolation
9.6 Spectral characteristic
9.7 Bioactivities
9.8 Examples of structure elucidation
References
10 Marine Natural Products
10.1 Introduction
10.2 Macrolides
10.3 Polyesters
10.4 Peptides
10.5 C15 acetogenins
10.6 Prostaglandin analogues
10.7 Sterols
10.8 Specific examples of marine products research
References
Index
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