- 心血管支架服役性能研究(英文版)
- - 作者：仇天阳|责编:多海鹏
  - 出版社：北京理工大学
  - ISBN：9787576314403
  - 出版日期：2022/06/01
  - 页数：253
- 售价：30.4

内容大纲
    新一代可降解血管支架，因其在完成狭窄血管的扩张和疏通作用后可自行降解消失，可降低长期滞留引起的并发症发生几率，减轻患者的心理压力，被认为是冠心病治疗领域的第四次革命。
    本书针对可降解血管支架结构设计、精密制造与性能评价等技术难题，系统介绍了可降解血管支架结构设计和扩张过程研究以及可降解血管支架生物降解机理研究，揭示支架单元结构参数对支架扩张变形性能的作用规律和加工参数对血管支架的生物降解过程的作用规律，实现可降解血管支架的优化设计，达到血管支架机械支撑力可调节，降解速度可调控，以及服役周期可预测的目的，为可降解血管支架的结构优化设计和精密制造提供理论支持。
    本书可作为高等院校工科相关专业师生的相关教材或参考书目，也可为科研人员提供参考。本书涉及机械、力学、生物学等学科内容，也可为跨学科领域科研人员提供重要参考。此外，本书为全英文撰写，可为相关领域的学生提供英文论文的写作指导。
作者介绍
目录
Chapter 1  Introduction for Cardiovascular Disease and Stent
  1.1  Coronary artery disease
  1.2  What is a stent
  1.3  Aim and objectives
Chapter 2 Review for Stent Technology
  2.1  Development of stents
    2.1.1  Bare metal stents (BMSs)
    2.1.2  Drug-eluting stents (DESs)
    2.1.3  Bioresorbable stents (BRSs)
    2.1.4  Conclusion
  2.2  Materials for bioresorbable stents
    2.2.1  Corrodible metallic alloys
    2.2.2  Biodegradable polymers
    2.2.3  Conclusion
  2.3  Arteries and atherosclerotic plaques
    2.3.1  Histological structures
    2.3.2  Mechanical behaviour
    2.3.3  Conclusion
  2.4  Experimental studies on stents
    2.4.1  Mechanical behaviour studies
    2.4.2  Degradation behaviour studies
    2.4.3  In vivo efficacy studies of polymeric stents
    2.4.4  Conclusion
  2.5  Computational work
    2.5.1  Stent expansion modelling
    2.5.2  Effects of stent designs
    2.5.3  Methods for modelling stent expansion
    2.5.4  Modelling of stent fatigue behaviour
    2.5.5  Stent degradation modelling
    2.5.6  Conclusion
  2.6  Research gaps
  2.7  Conclusions
Chapter 3 Methodology for Finite Element Simulation
  3.1  Finite element models
    3.1.1  Stent models
    3.1.2  Tri-folded balloon model
    3.1.3  Three-layered artery and plaque model
  3.2  Material constitutive models
    3.2.1  Constitutive models for stent and balloon
    3.2.2  Constitutive models for plaque and artery
  3.3  Finite element simulation setup
    3.3.1  Simulation procedures
    3.3.2  Post-processing of simulation results
  3.4  Mesh sensitivity study
    3.4.1  Stent mesh sensitivity
    3.4.2  Plaque-artery mesh sensitivity
  3.5  Conclusions
Chapter 4  Finite Element Modelling of Crimpingand Expansion of Bioresorbable Polymeric Stents
  4.1  Introduction
  4.2  Methodology

    4.2.1  Finite element models and material models
    4.2.2  Stent crimping procedure
    4.2.3  Stent expansion procedure
    4.2.4  Evaluation of the radial stiffness and strengthfor stent
  4.3  Results and discussions
    4.3.1  Stent crimping
    4.3.2  Stent expansion
    4.3.3  Residual stresses caused by crimping
    4.3.4  Radial stiffness and strength
  4.4  Conclusions
Chapter 5  Deployment of Bioresorbable Polymeric Stents in Stenotic Artery
  5.1  Introduction
  5.2  Methodology
    5.2.1  Finite element models and material constitutive models
    5.2.2  Crimping and expansion of stent in plaque-artery
  5.3  Results
    5.3.1  Stent expansion
    5.3.2  Stress variation on the plaque/artery
    5.3.3  Residual stress caused by crimping
  5.4  Discussions
  5.5  Conclusions
Chapter 6  Fatigue Behaviour of Bioresorbable
  6.1  Polymeric Stent
  6.2  Introduction
  6.3  Methodology
    6.2.1  FE models and constitutive models for stentand artery
    6.2.2  Simulation setup
  6.3  Results
    6.3.1  Stress/strain analysis
    6.3.2  Fatigue analysis
  6.4  Discussions
  6.5  Conclusions
Chapter 7Stent-Artery Interaction During Degradation and Vessel Remodelling
  7.1  Introduction
  7.2  Calibration of stress-strain curves duringdegradation
    7.2.1  Radial strength and stiffness of stent
    7.2.2  Calibration of stress-strain curves for PLLA during the degradation
  7.3  Modelling of stent-artery interaction duringdegradation
  7.4  Modelling of stent-artery interaction duringvessel remodelling
  7.5  Results
    7.5.1  PLLA stress-strain behaviour over degradation
    7.5.2  Stress variation on the stent over degradation
    7.5.3  Stress variation in the plaque-artery systemover degradation
    7.5.4  Effects of vessel remodelling
  7.6  Discussions
  7.7  Conclusions
Chapter 8  Poly (Lactic-Acid) and Poly (Butylene Succinate) Blends for Stent Application-Testing and Modelling
  8.1  Introduction
  8.2  Methodology
    8.2.1  Raw materials

    8.2.2  Preparation of PLA/PBS blends and specimens
    8.2.3  Characterization of PLA/PBS blends
    8.2.4  Mechanical testing
    8.2.5  Finite element modelling
  8.3  Results and Discussions
    8.3.1  DSC analysis
    8.3.2  Optical microscopy analysis
    8.3.3  Mechanical properties of PLA/PBS blends
    8.3.4  Rate dependent behaviour
    8.3.5  Effect of loading rate on stent behaviour
  8.4  Conclusions
Chapter 9 Conclusions and Further Work
  9.1  General conclusions
  9.2  Summary of key achievements
  9.3  Further work
    9.3.1  Experimental work
    9.3.2  Modelling work
References

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